Fig. 9
From: The BRD4 inhibitor JQ1 suppresses tumor growth by reducing c-Myc expression in endometrial cancer
JQ1 suppressed tumor growth in vivo in mouse xenograft models of endometrial cancer. Body weight (A) and tumor volume (B) from Ishikawa xenografts were measured every 2 days after treatment with JQ1. C Representative photographs of tumors dissected from xenografts after treatment with JQ1 for 3 weeks. D Tumor weight was determined at time of sacrifice in placebo and JQ1-treated groups. E Comparison of white blood cells (WBC) (109/L), erythrocytes (RBC) (1012/L), hemoglobin (Hb) (g/L) and platelet (PLT) (109/L) levels in control and JQ1-treated mice. Data are represented as mean ± SEM (n = 5)