Modulation of hepatic stellate cells by Mutaflor® probiotic in non-alcoholic fatty liver disease management

Table 1 The effect of NASH induction and probiotic administration on liver function tests and lipid profile

Groups	Control		12-week NASH		9-week NASH		Broth		3-week Treated		12-week Treated		F	p-value
Groups	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	F	p-value
SGOT	72.5	7	155.2	4.1	131.5	5.4	144.5	5.2	92.5	7.7	70.3	5.5	39	< 0.001**
SGPT	26.2	2.4	127.2	9.1	113.8	8.1	114.3	4.1	36.7	3.5	26.2	1.5	78	< 0.001**
GGT	13.8	1.8	66.5	3.8	72.8	3.6	71.8	4.5	25.0	1.1	17	1	94	< 0.001**
TB	0.4	0	1	0.2	1	0.2	1	0.1	0.4	0	0.4	0	8	< 0.001**
DB	0.1	0	0.3	0.1	0.3	0.1	0.3	0	0.2	0	0.1	0	8	< 0.001**
ALP	47.0	0.9	110.2	17.2	101.7	1.9	98.7	2.9	66.0	1.4	61.2	2.3	13	< 0.001**
T. Chole	144.9	2.5	253.6	11.3	228.5	8	246.6	12.7	137.8	4.1	139.5	3.9	49	< 0.001**
TG	52.7	2.9	182.2	9.7	169.2	7.5	166.3	13.4	92.5	5.2	75.7	4	49	< 0.001**
HDL	66.5	3	32.7	1.1	34.2	1.8	43.2	0.9	50.7	2.4	53.8	1.6	43	< 0.001**
LDL	67.8	2.5	184.5	9.4	160.5	7.3	170.2	11.9	68.7	2.2	70.5	3	64	< 0.001**

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