Fig. 5

The effect of NASH induction and Probiotic use on steatosis, inflammation and fibrosis of the liver using HE (A) and Masson’s trichrome staining (B) (Magnifications: ×100). Liver histological examinations showed both macro- and microvesicular steatosis, lobular inflammation, focal necrosis, hepatocellular ballooning, and extensive fibrosis (Arrow) in NASH models. These effects were minimized with Probiotic were remarkable especially in 12-week Treated model