Fig. 1

Asprosin prevents macrophages from lipid accumulation. A After incubation of THP-1 macrophages with or without 50 µg/mL ox-LDL for 48 h, qRT-PCR and western blot were used to detect asprosin expression (n = 3). B–D THP-1 macrophage-derived foam cells were transfected with LV-Mock or LV-Asprosin for 72 h (n = 3). B Protein samples were immunoblotted with antibodies against asprosin or β-actin. C The contents of intracellular TC, FC and CE were measured by HPLC. D Representative images of Oil red O staining. Data are expressed as mean ± SD. **P < 0.01, ***P < 0.001