Fig. 3

Pearson correlations between DNAm Age = epigenetic age calculated according to Horvath [9], TL = relative telomere length, mtDNAcontent = relative mitochondrial DNA content, globalmean = mean global DNA methylation, promotermean = mean methylation of the promoter gene-region, bodymean = mean methylation of the gene-body and intergenicmean = mean methylation of the intergenic region. In the top right corner, the correlation coefficients, and in the bottom left corner scatterplots of the correlation with regression line and 0.95% confidence interval are shown. The diagonal density plots display the distribution of observations. 5mC = 5-methylcytosine; mtDNA = mitochondrial DNA; nDNA = nuclear DNA; T/S = telomere/ single copy gene ratio * p < 0.05; ** p < 0.001