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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Reducing VEGFB accelerates NAFLD and insulin resistance in mice via inhibiting AMPK signaling pathway

Fig. 8

The suppression of VEGFB gene inhibits the AMPK/ACC/CPT1 signal pathway of fatty acid oxidation. A Western blot of p-ACC, ACC, CPT1 in NAFLD mice model were analyzed. B Protein level of p-ACC/ACC in NAFLD mice model. C Protein level of CPT1 in NAFLD mice model. D Western blot of p-ACC, ACC and CPT1 protein in NAFLD cell model were analyzed. E Protein level of p-ACC/ACC in NAFLD cell model. F Protein level of CPT-1 in NAFLD cell model. G mRNA level of CPT1α and Lcad in NAFLD mice model. H mRNA level of CPT1α and Lcad in NAFLD cell model. N = 6 cases per group. B, C, G *indicates vs. SD, p < 0.05; # indicates vs. HFD, p < 0.05; E, F, H * indicates vs. NC, p < 0.05

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