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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Reducing VEGFB accelerates NAFLD and insulin resistance in mice via inhibiting AMPK signaling pathway

Fig. 5

Systemic knockout of VEGFB accelerates liver injury in NAFLD mice. A Morphological pictures of mice liver tissue stained by HE and Masson. a indicates macrovesicular steatosis, b indicates vesicular steatosis, c indicates hypertrophic hepatocytes, d indicates inflammatory cell aggregates. B–E Percentage of hepatic bullous steatosis, vesicular steatosis, hypertrophic area of hepatocytes and number of inflammatory cell aggregates in mice liver tissue. F Score of hepatic bullous steatosis, vesicular steatosis, hypertrophic area of hepatocytes and inflammatory cell aggregates and total score of NAFLD. G, H TG and TCHO levels in liver tissue. I, J AST and ALT levels in mice serum. N = 8 cases per group. *indicates vs. SD, p < 0.05; # indicates vs. HFD, p < 0.05

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