Fig. 2

Construction and validation of the NRG signature. A LASSO Cox regression (with minimized lambda) of the differently expressed NRGs. B Forest plot showing the association between the expression level of 6 selected NRGs and the OS of patients. C Patient statuses and expression patterns for 6 selected NRGs in high- and low-risk groups of the training cohort. Kaplan–Meier (K-M) survival curve showing different OS (D), PFI (E), and DFS (F) in the two risk groups of the training cohort. G Patient statuses and expression patterns for 6 selected NRGs in high- and low-risk groups of the testing cohort. K-M survival curve showing different OS (H), PFI (I), and DFS (J) in the two risk groups of the testing cohort. *P < 0.05; **P < 0.01