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Table 1 Association between the clonal status of TP53 mutation and clinical features in colorectal cancer

From: Comprehensive characterization of clonality of driver genes revealing their clinical relevance in colorectal cancer

 

Clonal

Subclonal

WT

P-value

Age

 < 67.5(median)

153

9

103

0.346

 >  = 67.5(median)

139

14

113

 

Sex

 Female

129

17

108

0.015*

 Male

163

6

108

 

MSI status

 MSI

66

9

82

 < 0.001*

 MSS

225

14

133

 

Tumour site

 Right-sided

92

11

117

 < 0.001*

 Left-sided

193

11

90

 

AJCC stage

 Stage 1/Stage 2

134

16

141

 < 0.001*

 Stage 3/Stage 4

149

6

68

 

N stage

 N0

142

17

147

 < 0.001*

 N1/N2

150

6

67

 

T stage

 T1/T2

54

5

54

0.176

 T3/T4

238

18

160

 

M stage

 M0

206

15

169

0.016*

 M1

50

0

22

 
  1. Significant P values are labeled with *(P < 0.05). WT: wide type