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Table 1 The effects of MSCs and MSCs-EVs on tumors

From: TA-MSCs, TA-MSCs-EVs, MIF: their crosstalk in immunosuppressive tumor microenvironment

Species

Cell source

Type of tumor

Effects on tumor

experimental type

Reference numbers

Human

BM-MSCs-EVs

PC

Inhibition

In vitro and vivo

[23]

Human

BM-MSCs

MM

Inhibition

In vitro

[41]

Human

AD-MSCs

OC

Inhibition

In vitro

[24]

Human

UC-MSCs

HCC

Inhibition

In vitro

[253]

Human

UC-MSCs

LC

Inhibition

In vitro

[254]

Human

UC-MSCs

BC

Inhibition

In vitro and vivo

[255]

Human

UC-MSCs

Melanoma

Inhibition

In vitro and vivo

[22, 256]

Human

NLT-MSCs

LC

Promotion

In vitro and vivo

[26, 37]

Human

BM-MSCs

MM

Promotion

In vitro and vivo

[91]

Human

BM-MSCs

BC

Promotion

In vitro and vivo

[75, 92, 99, 194]

Human

BM-MSCs

Neuroblastoma

Promotion

In vitro and vivo

[43]

Human

AD-MSCs

BC

Promotion

In vitro and vivo

[76, 77, 88, 257]

Human

hESC-MSCs

BC

Promotion

In vitro

[222]

Human

AD-MSCs

Melanoma

Promotion

In vitro and vivo

[102]

Human

BM-MSCs

CRC

Promotion

In vitro and vivo

[78, 101, 208]

Human

UC-MSCs

LC

Promotion

In vitro

[20]

Human

UC-MSCs

BC

Promotion

In vitro and vivo

[223]

Human

UC-MSCs

GC

Promotion

In vitro and vivo

[21]

Human

BM-MSCs

CML

Promotion

In vitro and vivo

[86]

Human

BM-MSCs

PCa

Promotion

In vitro and vivo

[100, 113]

Human

BM-MSCs

GC

Promotion

In vitro and vivo

[196, 199, 208, 218]

Human

BM-MSCs

OS

Promotion

In vitro and vivo

[225, 231]

Human

BM-MSCs

Glioma

Promotion

In vitro

[227]

Human

BM-MSCs

Sacoma

Promotion

In vitro and vivo

[230]

Human

Oral-MSCs

KS

Promotion

In vitro and vivo

[232]

Human

AD-MSCs-EVs

BC

Promotion

In vitro

[44]

Human

BM-MSCs-EVs

NPC

Promotion

In vitro and vivo

[50]

Human

BM-MSCs-EVs

BC

Promotion

In vitro and vivo

[52, 92]

Human

BM-MSCs-EVs

CLL

Promotion

In vitro

[67]

Human

BM-MSCs-EVs

LC

Promotion

In vitro and vivo

[81]

Human

BM-MSCs-EVs

CRC

Promotion

In vitro and vivo

[101]

Human

UC-MSCs-EVs

GC

Promotion

In vitro and vivo

[80, 89]

Human

UC-MSCs-EVs

LC

Promotion

In vitro

[20]

Mouse

BM-MSCs

LC

Promotion

In vitro and vivo

[114, 158, 206]

Mouse

BM-MSCs

MM

Promotion

In vivo

[175]

Mouse

BM-MSCs

Glioma

Promotion

In vitro and vivo

[224]

Rabbit

BM-MSCs

PCa

Promotion

In vitro and vivo

[197]

Rat

BM-MSCs

Glioma

Promotion

In vitro and vivo

[226]