Fig. 5

Characterization and the targeting ability of RGD-Exo-circDIDO1. A The size distribution of RGD-Exo-circDIDO1 was detected by nanosight tracking analysis. B The morphology of exosomes was observed using a transmission electron microscope (scale bar = 40 nm). C The exosomal markers were analyzed by western blotting. D qRT-PCR analyses of circDIDO1 expression in RGD-Exo-circDIDO1. E The internalization of DiI-labeled RGD-Exo-circDIDO1 in GC cells was observed by confocal fluorescence microscope (scale bar = 20 μm). F qRT-PCR analyses of circDIDO1 expression in RGD-Exo-circDIDO1 treated GC cells. Data are shown as mean ± SD (n = 3, **P < 0.01, *P < 0.05)