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Table 1 Baseline characteristics and clinic-pathologic features of all patients

From: Whole-exome sequencing identified mutational profiles of urothelial carcinoma post kidney transplantation

Patient ID

Gender

Age at diagnosis

HBV/HCV

Chinese Herb history

Occupation

Kidney transplant

Induction

Maintenance

Acute rejection

Location

Tumor pathology

Treatment

KT17

F

48

No

Unknown

Bio-engineer

Yes

 

Tac + MMF + Pred

Yes

Bladder

Infiltrating UC high grade, pT3NoMx,

Partial cystectomy

KT79

F

61

No

Yes

Housewife

Yes

 

Tac + MMF + Pred

Yes

Bladder, ureter

Noninvasive UC,

high grade, pTa

Left nephrectomy

#KT80

F

51

HCV

Unknown

Housewife

Yes*

 

Tac + MMF + Pred + MTOR

No

Ureter (Lt)

Infiltrating UC high grade, pT2Nx,

Bilateral nephrectomy

KT81

F

63

HBV

Unknown

Housewife

Yes*

Steroid + IL2RA

Tac + MMF + Pred + MTORi

No

Renal Pelvis

Infiltrating UC high grade, pT2Nx,

Left nephrectomy

KT720

F

46

No

Unknown

Medical

Yes

 

Tac + MMF + Pred + MTORi

No

Renal Pelvis

Infiltrating UC, high grade, pT3

Right nephrectomy

#KT721

F

55

No

Unknown

Housewife

Yes*

 

Tac + MMF + Pred + MTOR

No

Bladder

Non-invasive papillary UC, high grade, pTa

TURBT

KT722

F

61

No

Unknown

Housewife

Yes

 

Tac + MMF + Pred

No

Renal Pelvis

Infiltrating UC,high grade, pT2aNx

Left nephrectomy

KT73

F

52

No

Unknown

Housewife

    

Bladder, ureter

Non-invasive Papillary UC, low grade

Right nephrectomy and cystectomy

KT77

F

56

HCV

Yes

Housewife

    

Bladder

Infiltrating UC,high grade, pT1Nx

Radical cystectomy and bilateral nephrectomy

KT78

F

70

No

Unknown

Sales person

No

N/A

N/A

N/A

Bladder + ureter

Infiltrating UC,

high grade, pT3aNx

Radical cystectomy

KT595

F

64

No

Yes

Worker

    

Renal Pelvis

Infiltrating UC, low grade, pT1NxMx

Left nephrectomy

KT596

F

66

No

Unknown

Housewife

    

Bladder

Non-invasive Papillary UC, high grade

Left nephrectomy

  1. Abbreviations: UC, Urothelial carcinoma; Tac, Tacrolimus; MMF, Mycophenolate myfortil; Pred, prednisolone; MTORi, Mammalian target of rapamycin inhibitors. N/A: not applicable
  2. *Transplant Tourism in Mainland China
  3. #KT80 and KT 721 sample are from the same patient at different time of surgery