Fig. 5

STAT6 transcriptionally activated the expression of SOX21-AS1 and SOX21. A AnnoLnc and JASPAR database predicted potential six transcription factors combined with SOX21-AS1 promoter. B, C The transfection efficiency of shRNAs targeting three transcription factors (STAT6, PAX6 and TCF3). D SOX21-AS1 expression in PC cells transfected with shRNAs targeting three transcription factors. E The binding sites of STAT6 on SOX21-AS1 promoter and SOX21 promoter. F ChIP data of the combining capabilities between P1, P2, P3 and P4 sites and STAT6. G The luciferase activity of P4-WT and P4-MUT in PANC-1 and SW1990 cells transfected with shRNAs targeting STAT6. ^**P < 0.01