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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21

Fig. 2

SOX21-AS1 regulated its nearby gene SOX21 at a post-transcriptional level. A GEPIA2 displayed the co-expressed gene with SOX21-AS1. B GEPIA2 displayed the correlation between SOX21-AS1 and SOX21, VILL, PLCD3 or LMO7 in PC. C, D The transfection efficiency of shRNAs targeting these four genes. E GEPIA 2 database displayed the relation between SOX21 expression and PC patients’ survival time. TCGA database displayed the expression of SOX21 in PC tissues. F UCSC database disclosed the location of SOX21-AS1 and SOX21 on the chromatin. G, H The cellular location of SOX21-AS1 in PC cells confirmed via FISH assay along with subcellular fractionation detection. **P < 0.01

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