Fig. 3From: Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat modelsCCR2 reduces depletion of proteoglycan in MIA rat. A Knee Joint tissue samples were collected from Mock and sCCR2-E3, sCCR2-Full rat at 14 day and subjected to stain with safranin O. B Stained tissues were assessed by Osteoarthritis Research Society International (OARSI) and Mankin scores. The data show the mean ± SEM of three independent experiments. (**p < 0.01, *** p < 0.001)Back to article page