Fig. 2
From: SLC26A4 correlates with homologous recombination deficiency and patient prognosis in prostate cancer
Profiling of HRD-related genes. A Distribution of prostate cancer samples according to HRD. Green dots meant the top HRD samples (Q1, > 75%), blue dots meant the bottom HRD samples (Q4, < 25%), red dots meant the medium HRD samples (Q2–3, 25% ~ 75%). B Volcano plot of differentially expressed genes between the top and bottom groups. C Forest plot of differentially expressed genes with significant prognostic value. Red block meant a risk effect (HR > 1), and blue block meant a protective effect (HR < 1). D Oncoplot showing the SNV mutation status of the TOP 10 HRD-related genes. E Dumbbell chart showing the CNV frequency of HRD-related genes. Red dots meant deletion frequency, and blue dots meant amplification frequency. F The expression differences of HRD-related genes between prostate cancer tissues and normal tissues. G The correlations among HRD-related genes. Red dots meant risk factors, and blue dots meant protective factors. The statistical significance is indicated as asterisks (*), *p < 0.05, ** p < 0.01, ***p < 0.001, ns: not significant