Fig. 5

iCAFs is associated with clinical prognosis and immune infiltration. A–D Box plots show the correlations between iCAFs and clinicopathologic features. E, F K-M survival plots show that high iCAFs predicted poor prognosis in TCGA COADREAD cohort, OS: overall survival, DSS: disease specific survival. G Forest map shows that iCAFs is an independent prognostic factor for OS. H Immunohistochemical analysis of PDGFRA expression in colorectal cancer or para-carcinoma tissues. I, J The diagrams show the relationships between iCAFs and immune score as well as stromal score. p value < 0.05 was considered as cut-off criteria