Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Spatial transcriptomics atlas reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment components in colorectal cancer

Fig. 2

CAFs-enriched subgroups are identified in CRC. A UMAP plot of unsupervised clustering result of tumor subclusters. B Heatmap of differentially expressed genes (DEGs) of different Tumor-subclusters. C Immunofluorescence analysis of specific proteins expression of iCAFs and mCAFs. D Heatmap of tumor microenvironment (TME) cell-type scores calculated by ssGSEA in tumor region. E KEGG enrichment functions of up-regulated genes in Tumor-subcluster 0. F Violin plots show the expression of tumor, inflammatory-cancer-associated fibroblasts (iCAFs) and myo-cancer-associated fibroblasts (mCAFs) markers in tumor region. G Heatmap of tumor microenvironment (TME) cell-type scores calculated by ssGSEA in fibroblast region

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us