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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: The abnormal expression of circ-ARAP2 promotes ESCC progression through regulating miR-761/FOXM1 axis-mediated stemness and the endothelial–mesenchymal transition

Fig. 7

circ-ARAP2 can influence EMT and cancer stem cells different by regulation miR-761/FOXM1. AC Images of tumor sphere formation assays in KYSE-150R and ECA-109R cell. Data are presented as mean ± SD; ***p < 0.001 vs. NC; ###p < 0.001 vs. si-circ-ARAP2. D, E RT-qPCR detection show the expression of stemness markers OCT4 and Nanog in KYSE-150R cells. Data are presented as mean ± SD; ***P < 0.001 vs. NC; ###p < 0.001 vs. si-circ-ARAP2. F, G RT-qPCR detection shows the relative expression of EMT relative E-cadherin and N-cadherin expression. Data are presented as mean ± SD; ***p < 0.001 vs. NC; ###p < 0.001 vs. si-circ-ARAP2

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