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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: The abnormal expression of circ-ARAP2 promotes ESCC progression through regulating miR-761/FOXM1 axis-mediated stemness and the endothelial–mesenchymal transition

Fig. 4

Knockdown of circ-ARAP2 suppressed ESCC metastasis. A Representative results showing the percentage of cells in G1, S, or G2 phase in ECA-109R cells by flow cytometry. B RT-qPCR were used to detected the expression of p21. Data are presented as the mean ± SD. ***p < 0.001 vs. NC. C, D Cellular migration was assessed in both KYSE-150R and ECA-109R cells using transwell assays. Data are presented as the mean ± SD. ***p < 0.001 vs. si-NC. E Living imaging detection show the ECA-109R cells pulmonary metastasis. FH The numbers of metastatic foci in lung tissues were caculation according to the HE staining. The data are expressed as the mean ± SD. ***p < 0.001 vs sh-NC

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