Fig. 1
The differential expression of circRNA in esophageal squamous cell carcinomas (ESCC). A Scatter plots used to evaluate the differential expression of circRNAs between ESCC tissues and the matched non-tumor tissues. B Volcano plots used to visualize the differential expression between two different groups. x-axis: log2 ratio of the level of circRNA expression between normal and tumor tissues. y-axis: the false discovery rate value (-log10 transformed) of the circRNAs. C Length distribution of the identified circRNAs. x-axis: the length of the circRNAs detected in this study. y-axis: the abundance of circRNAs classified by different lengths. D Heat map of all the differentially expressed circRNAs between normal and tumor tissues. E Relative expression of the 10 indicated circRNAs from ESCC tumor tissues and adjacent non-tumor tissues listed as measured by RT-qPCR. The data are presented as the mean ± SD. *p < 0.05; **p < 0.01. N, non-tumor tissues; T, tumor tissues