Fig. 6

PDBu reduced the expression of inflammatory factors and increased lipid transport in cultured macrophages. a Representative image of oil red O staining of ApoE^−/− + Saline, ApoE^−/−SDC4^−/− + Saline, ApoE^−/−SDC4^−/− + ox-LDL, and ApoE^−/−SDC4^−/− + ox-LDL + PDBu macrophages. b The levels of CE, FC, and TC in the supernatants of ApoE^−/− + Saline, ApoE^−/−SDC4^−/− + Saline, ApoE^−/−SDC4^−/− + ox-LDL, and ApoE^−/−SDC4^−/− + ox-LDL + PDBu macrophages were determined by ELISA (n = 5). c The levels of TNF-α, MCP-1, IL-8, IL-6, IL-2, and IL-1β in the supernatants of ApoE^−/− + Saline, ApoE^−/−SDC4^−/− + Saline, ApoE^−/−SDC4^−/− + ox-LDL, and ApoE^−/−SDC4^−/− + ox-LDL + PDBu macrophages were determined by ELISA (n = 5)