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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: A reduction of Syndecan-4 in macrophages promotes atherosclerosis by aggravating the proinflammatory capacity of macrophages

Fig. 4

KO of SDC4 promoted the expression of inflammatory factors and reduced lipid transport in cultured macrophages. a Representative image of oil red O staining of ApoE−/− and ApoE−/− SDC4−/− macrophages treated with or without ox-LDL. b The levels of CE, FC, and TC in the supernatants of ApoE−/− + Saline, ApoE−/−SDC4−/− + Saline, ApoE−/− + ox-LDL, and ApoE−/−SDC4−/− + ox-LDL cells were determined by ELISA (n = 5). c The levels of TNF-α, MCP-1, IL-8, IL-6, IL-2, and IL-1β in the supernatants of ApoE−/− + Saline, ApoE−/−SDC4−/− + Saline, ApoE−/− + ox-LDL, and ApoE−/−SDC4−/− + ox-LDL cells were determined by ELISA (n = 5)

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