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Table 3 Correlation analysis between eIF6 and relate genes and markers of innate immunity cells in ESCA

From: eIF6 is potential diagnostic and prognostic biomarker that associated with 18F-FDG PET/CT features and immune signatures in esophageal carcinoma

Description

Genemarkers

TIMER (n = 184)

GEPIA2 (n = 181)

Purity

None

Cor

p

Cor

p

Cor

p

Monocyte

CD14

 − 0.154

*

 − 0.132

0.073

 − 0.094

0.210

 

CD86

 − 0.286

*

 − 0.262

*

 − 0.230

*

 

CD16 (FCGR3A)

 − 0.238

*

 − 0.223

*

 − 0.190

*

TAM

CD68

0.139

0.062

0.156

*

0.140

0.061

 

CCL2

 − 0.266

*

 − 0.262

*

 − 0.130

0.077

 

CCL5

 − 0.117

0.116

 − 0.125

0.090

 − 0.081

0.280

M1 Macrophage

INOS (NOS2)

0.137

0.066

0.129

0.080

0.160

*

 

CXCL10

 − 0.129

0.083

 − 0.121

0.101

 − 0.018

0.800

 

TNF-α (TNF)

 − 0.029

0.695

 − 0.008

0.913

 − 0.028

0.710

M2 Macrophage

CD206 (MRC1)

 − 0.203

*

 − 0.200

*

 − 0.150

*

 

CD163

 − 0.208

*

 − 0.199

*

 − 0.094

0.210

 

IL10

 − 0.177

*

 − 0.182

*

 − 0.150

*

Neutrophils

CD66b (CEACAM8)

0.142

0.057

0.113

0.127

0.001

0.980

 

CD11b (ITGAM)

 − 0.189

*

 − 0.166

*

 − 0.170

*

 

CCR7

 − 0.039

0.601

 − 0.059

0.427

 − 0.180

*

 

CD15 (FUT4)

0.085

0.256

0.071

0.340

0.110

0.160

Natural killer cell

KIR2DL1

0.052

0.486

0.041

0.584

 − 0.090

0.230

 

KIR2DL3

 − 0.167

*

 − 0.159

*

 − 0.091

0.220

 

KIR2DL4

0.037

0.625

0.035

0.633

 − 0.025

0.740

 

KIR3DL1

0.022

0.766

0.013

0.858

 − 0.095

0.200

 

KIR3DL2

 − 0.107

0.153

 − 0.107

0.147

 − 0.029

0.700

 

KIR3DL3

 − 0.001

0.993

0.003

0.963

 − 0.048

0.520

 

KIR2DS4

0.041

0.586

0.053

0.470

 − 0.095

0.200

Dendritic cell

HLA-DPB1

 − 0.163

*

 − 0.165

*

 − 0.210

*

 

HLA-DQB1

 − 0.078

0.294

 − 0.093

0.210

 − 0.096

0.200

 

HLA-DRA

 − 0.129

0.083

 − 0.136

0.065

 − 0.110

0.130

 

HLA-DPA1

 − 0.137

0.065

 − 0.138

0.061

 − 0.130

0.070

 

BDCA-1 (CD1C)

 − 0.250

*

 − 0.249

*

 − 0.250

*

 

BDCA-4 (NRP1)

 − 0.213

*

 − 0.215

*

 − 0.100

0.170

 

CD11c (ITGAX)

 − 0.178

*

 − 0.168

*

 − 0.210

*

 

NKp46 (NCR1)

 − 0.031

0.681

 − 0.045

0.547

 − 0.100

0.170

  1. TAM, tumor associated macrophage; Cor, R value of Spearman’s correlation. Purity, correlation adjusted by purity. *p < 0.05. None, correlation without adjustment