Fig. 2From: Potential inhibitors for blocking the interaction of the coronavirus SARS-CoV-2 spike protein and its host cell receptor ACE2High through-put screening of the compound library. A The candidate compound FDA-03-23, tannic acid, can inhibit the combination of ACE2 and S-RBD greatly, was selected from 1280 kinds of compounds in FDA compound library. B TS984 (purple) is one of the compounds which can inhibit the combination of ACE2 and S-RBD. C The dose–effect curve of FDA-03-23. (EC50 = 49.71 µM). (D) The dose–effect curve of TS-984 (EC50 = 36.21 µM) and TS-1276 (EC50 = 16.38 µM)Back to article page