Fig. 2
From: Homoharringtonine is synergistically lethal with BCL-2 inhibitor APG-2575 in acute myeloid leukemia
HHT and APG-2575 synergistically inhibit AML cells growth. A Cell viability of AML cell lines (HL-60, Kasumi-1, MV4-11 and OCI-AML3) treated with APG-2575 and HHT single agent or their combination for 24 h. B The apoptosis of HL-60, Kasumi-1, MV4-11 and OCI-AML3 cells treated with APG-2575 and HHT single agent or their combination for 24 h. (One-way ANOVA, combination treatments versus control and single treatments, *P < 0.05; **P < 0.01; ***P < 0.001). C The levels of apoptosis related proteins were determined after drug exposure for 24 h