Table 2 COX model analysis based on METTL3 expression and patients’ clinical parameters
Variables | HR (95% CI) | P | HR (95% CI) | P |
|---|---|---|---|---|
Gender (male: female) | 0.929 (0.451 ~ 1.914) | 0.842 | 1.723 (0.763 ~ 3.888) | 0.190 |
Age (> 60: ≤ 60 years) | 3.117 (1.465 ~ 6.634) | 0.003 | 5.652 (2.348 ~ 13.609) | 0.000 |
Pathological stage (III + IV: I + II) | 5.028 (2.423 ~ 10.435) | 0.000 | 5.799 (2.389 ~ 14.075) | 0.000 |
Tumor size (≥ 5: < 5 cm) | 1.732 (0.829 ~ 3.618) | 0.144 | 0.991 (0.373 ~ 2.639) | 0.986 |
Tumor position (right: left) | 0.950 (0.469 ~ 1.921) | 0.885 | 0.809 (0.366 ~ 1.790) | 0.601 |
T stage (II + III: I) | 3.544 (1.731 ~ 7.259) | 0.001 | 3.849 (1.530 ~ 9.688) | 0.004 |
Distance metastasis (M1: M0) | 8.882 (1.954 ~ 40.372) | 0.005 | 3.745 (0.367 ~ 38.232) | 0.265 |
TNM stage (III + IV: I + II) | 3.433 (1.193 ~ 9.879) | 0.022 | 1.239 (0.256 ~ 5.986) | 0.790 |
METTL3 expression (high: low) | 2.379 (1.221 ~ 5.258) | 0.013 | 4.071 (1.624 ~ 10.208) | 0.003 |