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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Exosomes derived from myeloid-derived suppressor cells facilitate castration-resistant prostate cancer progression via S100A9/circMID1/miR-506-3p/MID1

Fig. 1

The circRNA expression profiles in MDSC-Exo-PC3 cells. A Hierarchical clustering analysis of circRNAs that were differentially expressed between MDSC-Exo-PC3 cells and control-PBS-PC3 cells. The red color represents high expression levels, whereas the green color represents low expression levels. B, C The relative expression of the four most upregulated (B) and four most downregulated circRNAs (C) were validated by qRT-PCR in MDSC-Exo-PC3 cells and control-PBS-PC3 cells. *P < 0.05; **P < 0.01; ***P < 0.001 vs. control-PBS-PC3. D Relative expression of circMID1 in benign prostatic hyperplasia (BPH; n = 31) and PCa tissues (n = 56) determined by qRT-PCR. E The circMID1 expression was detected between HSPC (n = 39) and castration-resistant prostate cancer (CRPC; n = 17) by qRT-PCR. All the experiments were performed at least three times. MDSC: myeloid derived suppressor cells

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