From: Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Source of exosomes | Intermediate molecule | Downstream pathway or molecule | Models or cells | Effect on downstream pathway | Refs. |
---|---|---|---|---|---|
MSC | NA | NA | focal cerebral ischemia | NA | [42] |
Adipose-derived MSCs | miR-25-3p | Autophagy | NA | – | [44] |
Endothelial progenitor cell | miR-137 | COX2/PGE2 | Oxyhemoglobin-treated SH-SY5Y cells | NA | [45] |
M2 microglia | miR-124 | USP14 | OGD | NA | [46] |
OGD preconditioned astrocytes | miR-92b-3p | NA | OGD | NA | [49] |
IPAS | circSHOC2 | miR-7670-3p/SIRT1 | MCAO | NA | [52] |
Astrocyte | microRNA-34c | TLR7, NF-κB/MAPK | I/R injury | NA | [53] |