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Table 1 Association between bacterial colonization and cancer development

From: Emerging role of human microbiome in cancer development and response to therapy: special focus on intestinal microflora

Bacteria

Types of tumor

References

Salmonella typhi

↑ Gallbladder cancer

Di Domenico et al. [212]

Helicobacter pylori

↑ Gastric cancer

Wang et al. [213]

Uropathogenic Escherichia coli

↑ Prostate cancer

Elkahwaji et al. [214]

Escherichia coli (strain CP1)

↑ Prostate cancer

Simons et al. [215]

Escherichia coli

↑ Bladder cancer

El-Mosalamy et al. [216]

Bacteroides vulgatus, Bacteroides stercoris

↑ Colorectal cancer

Hu et al. [79]

Lactobacillus acidophilus, Lactobacillus S06, and Eubacterium aerofaciens

↓ Colorectal cancer

Hu et al. [79]

Fusobacteria, Leptotrichia genus

↓ Pancreatic cancer

Fan et al. [217]

Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans

↑ Pancreatic cancer

Fan et al. [217]

↑↑↑ Enterotoxigenic Bacteroides fragilis

Colorectal cancer

Haghi et al. [218]

Zamani et al. [219]

↑↑↑ Fusobacterium nucleatum

Colorectal cancer

Chen et al. [220]

↑↑↑ Porphyromonas gingivalis, Fusobacterium nucleatum

Oral squamous cell carcinoma

Chang et al. [221]

↑↑↑ Enterobacteriaceae

Stomach cancer

Youssef et al. [222]

↓↓↓ Bifidobacteriaceae

Rectal neoplasm

Youssef et al. [222]

↑↑↑ Capnocytophaga, Veillonella (in saliva)

Lung cancer

Yan et al. [223]

  1. Some bacterial species diminished or raised the risk of various types of cancer as shown by the direction of the arrows, i.e., ↓ or ↑
  2. On the other hand, the comparison of the microbial composition between patients and healthy individuals revealed the higher/lower abundance of the bacterial population as indicated by ↑↑↑and ↓↓↓, respectively