Fig. 3

Effect of GANT and AFA, alone or in combination, on the death of MM cell lines. The death of human (H-Meso-1, MM-F1, MM-B1) and murine (#40a) cell lines was assessed by the Trypan blue assay after 24, 48, and 72 h of treatment with DMSO or GANT or AFA, alone or in combination. The results are expressed as the mean ± SD of two independent experiments performed in triplicate. Statistical significance of the effects obtained with GANT and AFA, alone or in combination, was calculated vs those obtained in (1) DMSO-, (2) GANT- and (3) AFA-treated cells with one-way ANOVA . ^×p < 0.05; *p < 0.01; ^#p < 0.001