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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X

Fig. 3

GATA2-AS1 and GATA2 promote CRC cell invasion, EMT and stemness. A The impacts of GATA2-AS1 or GATA2 depletion on CRC cell invasion were analyzed by transwell invasion assays. B The protein levels of EMT markers were measured in GATA2-AS1-shRNA or GATA2-shRNA transfected SW480 and HCT116 cells. C, D Western blot analysis and sphere formation assays measured the protein levels of stem cell markers (Nanog and OCT4) and the number and size of spheres were suppressed after GATA2-AS1 or GATA2 reduction. **P < 0.01

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Journal of Translational Medicine

ISSN: 1479-5876

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