Fig. 8

Differential genera identification and the differences in metabolic pathways in each group. LEfSe revealed differentially abundant genera at the gut (A) and lung (B) in all groups. The differences in metabolic pathways by PICRUSt functional analysis (C, D). Comparison of functional analysis of intestinal microbiota in three groups at COG and KEGG level 3 (C). Comparison of functional analysis of pulmonary microbiota in three groups at COG and KEGG level 3 (D). *P < 0.05, **P < 0.01