Identification of characteristic metabolic panels for different stages of prostate cancer by 1H NMR-based metabolomics analysis

Table 1 Participants’ pathological and clinical characteristics

Parameters		BPH^b	PCa^c	PCaB^d	p value^a
Parameters		BPH^b	PCa^c	PCaB^d	PCa vs BPH	PCaB vs BPH	PCaB vs PCa
N		75	62	50	–^e	–	–
Age (year)		65.15 ± 7.46	68.53 ± 7.58	73.82 ± 8.17	0.009	< 0.001	< 0.001
BMI (kg/m²)		24.10 ± 2.56	24.62 ± 2.56	23.38 ± 2.90	0.249	0.129	0.014
PSA (ng/mL)		12.64 ± 5.27	18.51 ± 15.92	401.16 ± 124.46	0.058	0.024	0.027
Gleason score	3 + 3	–	17	3
	3 + 4	–	11	8
	3 + 5	–	0	2
	4 + 3	–	22	10
	4 + 4	–	8	18
	4 + 5	–	2	6
	5 + 3	–	1	0
	5 + 4	–	1	2
	5 + 5	–	0	1

Data were presented as Mean ± SD
^aThe p values were calculated by using unpaired Student’s t-test with Bonferroni adjustment, the difference was considered to be statistically significant when p < 0.05
^bBPH, patient with benign prostatic hyperplasia
^cPCa, prostate cancer
^dPCaB, prostate cancer with bone metastasis
^eNo data.

ISSN: 1479-5876