Fig. 4

The predictive performance of SubP28 signature and immune infiltration association. A The K-M plot of SubP28 signature in independent testing sets from CGGA, PCAWG, and TCGA databases. B The SubP28 score in the Ivy Glioblastoma Atlas Project. Each column annotates subpathway activity in RNA-seq of an anatomically defined tumor compartment. C The associations between SubP28 signature and other microglia signatures of C8 gene sets from MsigDB database. D The associations of SubP28 score with GBM samples with different molecular sub-types and LGG samples with IDH1 mutation event. E The associations between SubP28 score and immune infiltration characterization