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Table 3 Adjusted hazard ratios and 95% confidence intervals for diabetes risk associated with the lipid parameters in different test populations: sensitivity analysis

From: Evaluation of the value of conventional and unconventional lipid parameters for predicting the risk of diabetes in a non-diabetic population

 

HR (95% CI)

Sensitivity-1

Sensitivity-2

Sensitivity-3

HDL-C

0.63 (0.41, 0.99)

0.49 (0.29, 0.82)

0.50 (0.34, 0.75)

TC

0.99 (0.86, 1.14)

0.89 (0.73, 1.08)

0.97 (0.85, 1.10)

TG

1.17 (1.01, 1.34)

1.24 (1.00, 1.52)

1.30 (1.15, 1.46)

LDL-C

1.00 (0.85, 1.19)

0.94 (0.75, 1.18)

0.98 (0.84, 1.14)

Non-HDL-C

1.04 (0.90, 1.20)

0.99 (0.81, 1.20)

1.04 (0.92, 1.19)

RC

1.64 (0.98, 2.74)

1.74 (0.82, 3.72)

2.25 (1.44, 3.53)

TC/HDL-C ratio

1.10 (1.00, 1.21)

1.17 (1.01, 1.35)

1.15 (1.05, 1.26)

TG/HDL-C ratio

1.14 (1.02, 1.27)

1.19 (1.03, 1.37)

1.23 (1.13, 1.34)

Non-HDL/HDL-C ratio

1.10 (1.00, 1.21)

1.17 (1.01, 1.35)

1.15 (1.05, 1.26)

LDL/HDL-C ratio

1.11 (0.98, 1.26)

1.20 (1.00, 1.44)

1.16 (1.03, 1.29)

RC/HDL-C ratio

3.69 (1.09, 12.47)

14.01 (2.75, 71.47)

7.73 (2.68, 22.28)

  1. Note 1: (1) sensitivity-1: subjects with a follow-up of less than 3 years were excluded (n = 11,237); (2) sensitivity-2: subjects diagnosed with fatty liver at baseline were excluded. (n = 12,823); (3) sensitivity-3: excluding subjects whose SBP ≥ 140 mmHg or DBP ≥ 90 mmHg (n = 14,878);
  2. Note 2: sensitivity-1 adjusted for sex, age, BMI, habits of exercise, drinking status, smoking status, fatty liver, SBP, FPG, HbA1c, height, ALT, AST and GGT. Sensitivity-2 adjusted for sex, age, BMI, habits of exercise, drinking status, smoking status, SBP, FPG, HbA1c, height, ALT, AST and GGT. Sensitivity-3 adjusted for sex, age, BMI, habits of exercise, drinking status, smoking status, fatty liver, FPG, HbA1c, height, ALT, AST and GGT
  3. HR hazard ratios; CI confidence interval; other abbreviations as in Table 1
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Journal of Translational Medicine

ISSN: 1479-5876

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