Fig. 4

Independent validation of the miRNA models in the validation cohort. A, B Quantitative analysis of circulating miR-30a-5p (A) and miR-654-5p (B) in additional 50 HF patients and 25 controls (Ctrl) in the validation phase. C Diagnostic accuracy, AUC and 95% CI of the three models tested in the subjects of the validation cohort. D–F Receiver operating characteristic (ROC) curves of the three models in the validation cohort