Comparison of dynamic susceptibility contrast enhanced MR and FDG-PET brain studies in patients with Alzheimer’s disease and amnestic mild cognitive impairment

Table 3 Comparison of MR perfusion and FDG-PET results from different cortical locations between AD, MCI and control groups

Cortical location	Mean rCBV							rCBV z-score			PET z-score
	Study groups			ANOVA	Sheffeʼs post-hoc test			Study groups		Sheffeʼs post-hoc test	Study groups		Sheffeʼs post-hoc test
	AD (SD)	MCI (SD)	CG (SD)	p value	AD vs CG p value	MCI vs CG p value	AD vs MCI p value	AD (SD)	MCI (SD)	AD vs MCI p value	AD (SD)	MCI (SD)	AD vs MCI p value
R frontal	0.90 (0.11)	1.09 (0.19)	1.18 (0.17)	< 0.001*	< 0.001*	0.22	< 0.001*	1.64 (0.66)	0.51 (1.55)	< 0.001*	1.55 (1)	0.9 (0.44)	< 0.001*
L frontal	0.86 (0.1)	1.09 (0.22)	1.18 (0.13)	< 0.001*	< 0.001*	0.26	< 0.001*	2.44 (0.83)	0.65 (1.66)	< 0.001*	1.93 (1.25)	0.97 (0.49)	< 0.001*
R temporal	0.85 (0.09)	1.11 (0.18)	1.29 (0.3)	< 0.001*	< 0.001*	0.013*	< 0.001*	1.4 (0.29)	0.57 (0.61)	< 0.001*	2.24 (0.86)	1.02 (0.4)	< 0.001*
L temporal	0.85 (0.1)	1.09 (0.17)	1.3 (0.4)	< 0.001*	< 0.001*	0.01*	< 0.001*	1.12 (0.24)	0.52 (0.43)	< 0.001*	2.52 (0.96)	1.01 (0.47)	< 0.001*
R parietal	0.83 (0.09)	1.08 (0.18)	1.23 (0.14)	< 0.001*	< 0.001*	0.005*	< 0.001*	2.9 (0.68)	1.08 (1.33)	< 0.001*	2.5 (1.1)	1.31 (0.58)	< 0.001*
L parietal	0.81 (0.10)	1.08 (0.20)	1.24 (0.16)	< 0.001*	< 0.001*	0.008*	< 0.001*	2.64 (0.6)	0.95 (1.2)	< 0.001*	2.73 (1.23)	1.29 (0.61)	< 0.001*
R PCG	0.8 (0.11)	1.06 (0.22)	1.2 (0.22)	< 0.001*	< 0.001*	0.056	< 0.001*	1.83 (0.53)	0.64 (1.02)	< 0.001*	1.84 (0.71)	0.94 (0.58)	< 0.001*
L PCG	0.79 (0.11)	1.09 (0.22)	1.24 (0.23)	< 0.001*	< 0.001*	0.040*	< 0.001*	1.96 (0.48)	0.64 (0.94)	< 0.001*	2.12 (0.73)	1.03 (0.55)	< 0.001*

SD standard deviation, R right, L left, PCG posterior cingulate gyrus, AD Alzheimer’s disease, MCI mild cognitive impairment, CG control group, rCBV relative cerebral blood volume
*Statistically significant values, p < 0.05

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