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Table 1 Demographic characteristics and comorbidities of patients newly diagnosed with chronic fatigue syndrome in Taiwan between 2000 and 2012 and of those in the control group

From: Treatments of chronic fatigue syndrome and its debilitating comorbidities: a 12-year population-based study

Variable CFS cohort Non-CFS cohort P-value
(n = 6306) (n = 6306)
Gender    > 0.99
 Female 3339 (52.9) 3339 (52.9)  
 Male 2967 (47.1) 2967 (47.1)  
Age at diagnosis of CFS    > 0.99
 ≤ 34 1350 (21.4) 1350 (21.4)  
 35–64 3485 (55.3) 3485 (55.3)  
 ≥ 65 1471 (23.3) 1471 (23.3)  
Age at diagnosis of CFS(mean, SD)† 50.6 (17.9) 50.6 (18.0) 0.80
Comorbidity    
 Depression 807 (12.8) 407 (6.45) < 0.0001
 Anxiety disorder 2038 (32.3) 1033 (16.4) < 0.0001
 Insomnia 2303 (36.5) 1106 (17.5) < 0.0001
 Suicide 19 (0.30) 12 (0.19) 0.20
 Crohn's disease 255 (4.04) 121 (1.92) < 0.0001
 Ulcerative colitis 279 (4.42) 138 (2.19) < 0.0001
 Renal disease 585 (9.28) 427 (6.77) < 0.0001
 T1DM 78 (1.24) 68 (1.08) 0.40
 T2DM 1473 (23.3) 1068 (16.9) < 0.0001
 Obesity 93 (1.47) 64 (1.01) 0.01
 Gout 1196 (18.9) 702 (11.1) < 0.0001
 Dyslipidemia 2252 (35.7) 1356 (21.5) < 0.0001
 Malignancy 407 (6.45) 487 (7.72) 0.01
 HIV 3 (0.05) 3 (0.05) > 0.99
 Rheumatoid arthritis 254 (4.03) 155 (2.46) < 0.0001
 Psoriasis 94 (1.49) 83 (1.32) 0.40
 Ankylosing spondylitis 53 (0.84) 39 (0.62) 0.14
 Lymphadenopathy 132 (2.09) 104 (1.65) 0.06
 Hashimoto's thyroiditis 13 (0.21) 10 (0.16) 0.53
 Sjogren's syndrome 110 (1.74) 71 (1.13) 0.003
 Irritable bowel syndrome 886 (14.1) 423 (6.71) < 0.0001
 Fibromyalgia 4905 (77.8) 4914 (77.9) 0.85
 SLE 4 (0.06) 9 (0.14) 0.16
 Herpes zoster 341 (5.41) 234 (3.71) < 0.0001