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Table 1 Testing set sample information

From: A dPCR-NIPT assay for detections of trisomies 21, 18 and 13 in a single-tube reaction-could it replace serum biochemical tests as a primary maternal plasma screening tool?

Clinical samples sorted by

T21

T18

T13

Normal

Total

Maternal age (Years)

     

  ≤ 24

4

1

0

27

32

 25–34

17

7

1

169

194

 ≥ 35

4

2

0

51

57

Gestational age (Weeks)

     

 12–15

17

9

1

28

55

 16–20

7

1

0

191

199

 21–25

0

0

0

17

17

 ≥ 26

1

0

0

11

12

Screen method

     

 SBT HR (Cut-off at 1/270)

5

0

0

38

43

 SBT IR (Cut-off at 1/271–1/1000)

3

0

0

63

66

 Abnormal Ultrasound Results

15

9

1

23

48

 Adv. Maternal Age (≥ 35 Years)

1

0

0

47

48

 Direct NGS-NIPT

1

1

0

76

78

Total

25

10

1

247

283