Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: C2orf40 inhibits metastasis and regulates chemo-resistance and radio-resistance of nasopharyngeal carcinoma cells by influencing cell cycle and activating the PI3K/AKT/mTOR signaling pathway

Fig. 2

Overexpression of C2orf40 impairs the migration ability of NPC cells in vitro. A Gene set enrichment analysis (GSEA) was performed using two GEO datasets (GSE12452 and GSE53819) which compared high C2orf40 expression group and low C2orf40 expression group. The results showed the most significant enrichment of the cell migration-related genes in the high C2orf40 expression group. B The migration of HONE-1 and SUNE-1 cells stably overexpressing C2orf40 was assessed by in vitro scratch wound-healing assay. C The effects of C2orf40 overexpression on the migration and invasion abilities of SUNE-1 and HONE-1 cells were investigated via transwell migration and invasion assays. The experiments were performed in triplicate and repeated twice. Data are presented as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us