Fig. 3
From: Identifying the critical states and dynamic network biomarkers of cancers based on network entropy
The dynamic network change of LNE genes in KIRC, LUSC, STAD and LIHC. A In KIRC, the LNE gene group/module evolved, and there was a significant change in the network structure at stage III. B Similarly, the network LNE score significantly changed at stage IIA in LUSC. C The network LNE score significantly changed at stage IIIA in STAD. D The network LNE score significantly changed at stage II in LIHC. The network structure was derived by mapping LNE genes to the STRING PPI network. We discarded all the isolated nodes without any links to other nodes. The color of each node denotes the value of the scaled local LNE score, while the color of each edge denotes the absolute value of the Pearson correlation coefficient \(|{\text{PCC}}|\)