\ | Gene name | Ratio | Obs. rank | Sim. rank | Annotation | Loc | Function | Refs |
---|---|---|---|---|---|---|---|---|
1 | TRAPPC9 | 0.07 | 5891 | 2 | trafficking protein particle complex 9 | PM | NF-kappa-B signaling | [19] |
2 | LPP | 0.11 | 3611 | 11 | LIM domain containing preferred translocation partner in lipoma | NU | Localized at focal adhesions and cell–cell contact sites; shuttles to the nucleus where it affects transcription | |
3 | ELFN2 | 0.12 | 4446 | 13 | extracellular leucine-rich repeat and fibronectin type III domain containing 2 | UK | Unknown | – |
4 | ANKLE2 | 0.13 | 3107 | 16 | ankyrin repeat and LEM domain containing 2 | NU | Mitosis | |
5 | SHROOM3 | 0.14 | 4931 | 28 | shroom family member 3 | CY | Regulating cell shape in certain tissues | |
6 | PGR | 0.14 | 3798 | 27 | progesterone receptor | NU | Regulation of gene expression and affect cellular proliferation and differentiation in target tissues | |
7 | MAP1B | 0.15 | 6400 | 39 | microtubule-associated protein 1B | CY | Microtubule assembly | |
8 | OBSL1 | 0.15 | 5649 | 38 | obscurin-like 1 | PM | Links internal cytoskeleton to cell membrane | |
9 | CELSR1 | 0.15 | 6483 | 57 | cadherin, EGF LAG seven-pass G-type receptor 1 | PM | Involved in cell adhesion | |
10 | DBNL | 0.16 | 5544 | 50 | drebrin-like | CY | For organ development and immune response. Promote proliferation, colony formation, migration, invasion | |
11 | PHF21A | 0.16 | 3552 | 36 | PHD finger protein 21A | NU | Repression of neuron-specific genes through repressor element-1 or neural restrictive silencer | |
12 | TRPV6 | 0.16 | 5245 | 48 | transient receptor potential cation channel, subfamily V, member 6 | PM | Calcium channels required for assembly and regulation | |
13 | VEGFA | 0.16 | 4406 | 47 | vascular endothelial growth factor A | ES | Angiogenesis, endothelial cell growth, cell migration, apoptosis | [64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84] |
14 | GRIP2 | 0.17 | 3298 | 51 | glutamate receptor interacting protein 2 | OM | Bind AMPA receptors and target AMPA receptors to synapses | |
15 | RALGDS | 0.17 | 4874 | 61 | ral guanine nucleotide dissociation stimulator | CY | effectors of Ras-related GTPases that participate in signaling | |
16 | CCDC144A | 0.17 | 4302 | 58 | coiled-coil domain containing 144A | UK | Unknown | – |
17 | RAI1 | 0.17 | 3399 | 55 | retinoic acid induced 1 | CY | associated with severity and response to medication in schizophrenia patients | |
18 | TBC1D2B | 0.17 | 3106 | 52 | TBC1 domain family, member 2B | UK | Unknown | – |
19 | SMG1 | 0.17 | 5523 | 82 | smg-1 homolog phosphatidylinositol 3-kinase-related kinase | CY | Involve in tumorigenesis as a new tumor suppressor | |
20 | BRWD1 | 0.18 | 4873 | 85 | bromodomain and WD repeat domain containing 1 | NU | Unknown | – |