Fig. 9

Imputed drug sensitivity score of necroptosis-related phenotype. A The number of drugs in GDSC v2 that was significantly upregulated or downregulated (P < 0.05) in the high-risk score group versus low-risk score group among each of 24 drug categories in the TGCA cohort. B Barplot shows the imputed drug sensitivity score between high- and low-risk groups. The statistical difference of two clusters was compared through the Wilcox test. *P < 0.05; **P < 0.01; ***P < 0.001. C Dot plot shows the imputed drug sensitivity score among three NRCs. D Barplot shows the imputed drug sensitivity score among three NRCs. The statistical difference of three clusters was compared through the Kruskal–Wallis H test. *P < 0.05; **P < 0.01; ***P < 0.001