Fig. 5

Single-cell analysis of necroptosis-based classification in CRC. A Venn plot shows overlapped genes between NRC1, gene-cluster A and NRGs. B UMAP plot show score α in 47,285 single cells of SMC cohort. C Box-plot shows score of two signatures in different cell types of SMC cohort. The statistical difference of two groups was compared through the Wilcox test. *P < 0.05; **P < 0.01; ***P < 0.001. D Venn plot shows overlapped genes between NRC3, gene-cluster D and NRGs. E UMAP plot shows score β in 47,285 single cells of SMC cohort. F UMAP plot shows score α and β in 19,796 epithelial cells of GSE178318. G Box-plot shows score of two signatures in different sites of GSE178318. The statistical difference of two groups was compared through the Wilcox test. *P < 0.05; **P < 0.01; ***P < 0.001