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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Bulk and single-cell transcriptome profiling reveal necroptosis-based molecular classification, tumor microenvironment infiltration characterization, and prognosis prediction in colorectal cancer

Fig. 1

Landscape of genetic variation of necroptosis-related genes in colorectal cancer. A A flowchart of our study. B Gene ontology annotation of necroptosis-related genes. C Oncoplot show genetic alterations of 33 NRGs in CRC. The number on the right indicated the mutation frequency in each gene. Each column represented individual patients. D CNV frequency of 33 NRGs in CRC tumors. E Locations of CNV alterations in NRGs on 23 chromosomes. F Principal component analysis of necroptosis-related genes to distinguish tumors from normal samples in TCGA-COAD/READ cohort. All samples: n = 626; tumor: n = 578; normal: n = 48. G Expression distributions of 33 NRGs between normal and CRC tissues

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Journal of Translational Medicine

ISSN: 1479-5876

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