Table 3 Top list of possible canonical pathways associated with 23 miRNAs which differentially expressed in patients with IMN-R
KEGG Pathway | Total genes in pathway | miRNAs | p-value |
|---|---|---|---|
Proteoglycans in cancer | 95 | 17 | 1.25E−07 |
TGF-beta signaling pathway | 46 | 15 | 2.26E−07 |
Long-term depression | 35 | 15 | 2.26E−07 |
Hippo signaling pathway | 73 | 16 | 2.26E−07 |
Prion diseases | 12 | 11 | 7.45E−07 |
Transcriptional misregulation in cancer | 84 | 18 | 1.02E−06 |
Glioma | 38 | 15 | 2.42E−06 |
Renal cell carcinoma | 43 | 15 | 4.93E−06 |
Chronic myeloid leukemia | 45 | 15 | 4.99E−06 |
FoxO signaling pathway | 73 | 16 | 6.65E−06 |
Axon guidance | 68 | 15 | 1.45E−05 |
Acute myeloid leukemia | 36 | 14 | 1.66E−05 |
Pathways in cancer | 178 | 17 | 1.67E−05 |
Rap1 signaling pathway | 105 | 18 | 2.48E−05 |
Viral carcinogenesis | 83 | 18 | 2.60E−05 |
Adherens junction | 44 | 16 | 4.85E−05 |
Colorectal cancer | 40 | 15 | 9.85E−05 |
Signaling pathways regulating pluripotency of stem cells | 69 | 17 | 0.000102 |
Focal adhesion | 102 | 15 | 0.000137 |
Non-small lung cancer | 32 | 15 | 0.000151 |