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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: The progression rate of spinocerebellar ataxia type 3 varies with disease stage

Fig. 1

The trajectory and average progression rates of ICARS over the studied period. A showed the actual trajectory of ICARS for each participant. The purple line depicted the average progression rate from LM1 model with single-slope, with black lines showing the average progression rate from PM1 model with two-segment slopes. Dots were plotted for each subject indicating actual ICARS scores (y-axis) versus disease duration (x-axis). The blue dots and lines represented early disease stage, with red dots and lines for late stage. B showed the predicted trajectory of ICARS for each participant using the optimal PM4c growth model. Different colored dots and lines represented predicted ICARS scores (y-axis) versus disease duration (x-axis) for different subjects

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