Fig. 2From: 5-fluorouracil treatment of patient-derived scaffolds from colorectal cancer reveal clinically critical informationGenetic response of HT29 cells cultured in 2D, PDS and Matrigel to 5FU treatment. A Principal component analysis of gene expression data of HT29 cells cultured in 2D (grey symbols), PDS (blue sympols) and Matrigel (red symbols) and treated with increasing concentrations of 5FU. Data is expressed relative to untreated 2D-cultured HT29 cells. B qPCR data showing gene expression before and after 10 mM 5FU treatment in HT29 cells cultured in 2D, PDS and Matrigel. Data is expressed relative to untreated 2D cells. Bars represent Mean ± SEM, *p < 0.05, **p < 0.01, Student’s t testBack to article page