Fig. 7

NACC1 activated the AKT/mTOR pathway in OC cells. A, B RT-qPCR was used to detect the expression of AKT and mTOR in OC tissues and benign ovarian tumor tissues; C–F Pearson analysis was used to assess the correlation of miR-18a-5p/NACC1 with the AKT/mTOR pathway; G, H WB was employed to measure the levels of p-AKT, AKT, p-mTOR, and mTOR in cells. Cell experiments were repeated 3 times. Data were expressed as mean ± SD. One-way ANOVA was adopted for comparisons between groups and Tukey's multiple comparisons test was performed for the post hoc test. *P < 0.05,**P < 0.01, ***P < 0.001